International Conference on Biological Information and Biomedical Engineering (BIBE2018)

Latest Accepted Papers (Update time: March 21^st, 2018)

BIBE16651: Detection of gold nanoparticles in complex matrices by SP-ICP-MS
GONG Zi-Shan, HAN Wen-Nian, SUN Chuan-Qiang, etc.
Abstract: Along with the quick development of science and technology, nanotechnology has attracted much attention in recent years. A reliable method for detecting nanoparticles is necessary to…

BIBE16775: Detection and Identification of Hemorrhages in Fundus Images of Di-abetic Retinopathy
Lipin Li and Mehmet Celenk
Abstract: Diabetic retinopathy (DR) is a progressive eye complication of diabetes which may cause sight loss and blindness if not detected and treated in time. Hemorrhage is one of the early signs…

BIBE11000: Study of the Distinguishability of Electrical Impedance Scanning System Based on the FEM Model
Ruiqing WANG, Xuetao SHI, Feng FU, etc.
Abstract: Objective: The distinguishability of Electrical impedance scanning (EIS) determines the clinical diagnosis accuracy. To direct the EIS clinical application, it is important to investigate the…

BIBE16063: Classification between mental arithmetic and motor imagery based on historical data, a study of brain-computer interface using functional near-infrared spectroscopy
Jian' ai Ma, Ling Wang, Yizhu Tian, etc.
Abstract: Recent years, the functional near-infrared spectroscopy (fNIRS) has been more and more recognized as an important approach for brain computer interface (BCI) due to its advantages…

BIBE15632: Bioinformatics Analysis of Gene Regulatory Network in Cardiac De-velopment
XINYUE ZHANG, YUHAN WANG, JINGSHU ZHANG, etc.
Abstract: This research aims at exploring the differential expression of genes that relating to CHD (congenital heart disease) and analyzing genes in bioinformatics way. Genes that may associated…

BIBE19315: Molecular Dynamics Simulation Study of the Interaction between Estrogen Receptor β and the Effective Components of Asarum
Zhang Lilei, Liu Xiaojie, Zhang Jingxiao
Abstract: The targeted agonist of estrogen receptor β was predicted from the effective components of Asarum, which is a famous Chinese herbal medicine. In addition, the interactions between…

BIBE15949: Study on magnetoencephalography of depression based on approximate entropy and sample entropy
Hui Hu, Jun Wang, Wei Yan, etc.
Abstract: In this paper, approximate entropy and sample entropy are applied to the study of magnetoencephalography, the entropy of the magnetoencephalography of the depressive and normal…

BIBE11601: Design and Kinematic Analysis of Positioning Chair for Proton Heavy Ion Radiotherapy
Yong-de Zhang, Zhi-kang Yang, Shi-jie Guo
Abstract: In the treatment room of proton heavy ion fixed beam, the proton heavy ion therapy chair assists the patient to complete the sitting position, so that the ion beam can be irradiated from…

BIBE12281: Automatic ECG-Based Seizure Prediction VLSI System with Pipelined Support Vector Machine
Hailong Bai, Zunchao Li, Lichen Feng, Chen Jiao, Lvchen Zhou
Abstract: This paper proposes a new VLSI seizure prediction system through integrating heart rate variability (HRV) analysis and machine learning technique. The prediction of epilepsy seizure based on…

BIBE13118: Significant difference of the culturable anaerobic microbial species in GujingTribute pitmud with different ages
Junwei Li, Hongkui He, Runjie Cao, Anjun Li and Zhizhou Zhang
Abstract: Most Chinese liquor belongs to strong-aroma type, and GujingTribute liquor with a history over 1800 years is one of this type. The flavor of strong-aroma Chinese liquor is largely determined…

BIBE15451: Using barnacle-specific primers to quantify larva attachment on nano-filled coatings during the early stages of marine biofouling
Zhengyu Yan, Changlu Guo, Zhizhou Zhang, Shan Gao
Abstract: This study tried to set up an approach to quantify the attached barnacle larvae in marine biofilms. Biofilms were collected from nano-filled coatings that previously characterized with different…

BIBE14098: Deep Learning Framework for Hemorrhagic Stroke Segmentation and Detection
Yan Wang, Heng Liu, Yi Liu, Weiping Liu
Abstract: This work presents a deep learning framework on Tensorflow for hemorrhagic stroke segmentation and detection from CT scans and corresponding 3D masks created by combining…

BIBE18874: Comparison between medical knowledge based and computer auto-mated feature selection for detection of coronary artery disease using imbalanced data
Han Li, Xinpei Wang, Yang Li, Caijie Qin, Changchun Liu
Abstract: This paper investigated the differences between medical knowledge based and computer automated feature selection with an imbalanced dataset of coronary artery disease (CAD). Sub-data sets…

BIBE18523: Gene ontology tree analysis integrated with tendency cluster for deep sequencing database to interpret the mechanism of classical swine fever virus infection
Xiaocheng Gong, Aoxue Hu, Xuepeng Li, etc.
Abstract: Classical swine fever (CSF), inducing significant economic losses to the global pig breeding industry, is caused by classical swine cause fever virus (CSFV). Macrophage is one of main…

BIBE16493: Absolute measurement of tissue oxygen saturation with NIRS
Jingyi Zhu, Jian Mou, Jun Liu
Abstract: In order to avoid irreversible damage caused by tissue hypoxia, the regional tissue oxygen saturation (rSO2) should be monitored to ensure the normal tissue oxygen metabolism. Near infrared…

BIBE14942: Effect of Aluminium oxide on inhibition activity of a deep-sea Penicillium sp. against Aspergillus parasiticus
Li wei, Yan pei-sheng, Shi cui-juan, Zhou ying, Gao xiu-jun, Li meng-ying
Abstract: In this study, the effects of aluminium oxide content, microparticle diameter and rotational speed on the activity of fermentation broth of deep-sea Penicillium MHE1 in inhibiting the…

BIBE15820: A Non-mixture Cure Model for Right Censored Data with Fréchet Distribution
Durga H. Kutal and Lianfen Qian
Abstract: This paper considers a non-mixture cure model for right censored data. It utilizes the maximum likelihood method to estimate model parameters in the non-mixture cure model. The simulation study is based on…

BIBE11371: A Multifunctional Theranostic Platform Based on Peptide Modified Dendrimer for Image-guided Drug Delivery and Anticancer Therapy
Jie Cao, Ruifen Ge, Yan Liang, Shangcong Han, Tingting Zhang, Yong Sun
Abstract: Theranostics, where both diagnosis and therapy is simultaneously realized, has become a newly emerging field in recent years, and can be used as an individualized approach to tumor patients. Combination of photothermal (PTT) and…

BIBE12342: Research on Exercise Load Quantification of School Children Based on Intensity Coefficient Method
Zhang Kuixing, Song Xiaoxiao, Wu Shuicai, et al.
Abstract: The purpose of the article is to explore the scientific monitoring and evaluation methods of the key links of the physical exercise load of primary and secondary school students. A total of 297 pupils from different…

BIBE18649: A Memory Mechanism Based on Two Dimensional Code of Neuro-some Pattern
Shengyong Xu, Jingjing Xu
Abstract: How memories are stored and retrieved is an important question. Here we present a model for the material foundation of memory, which is based on basic facts. We recognized that two-dimension (2D) codes…

BIBE18898: Application of curve fitting in electromagnetic tracking of electronically controlled rotating magnetic field
Chang Sheng, Xiaomei Wu
Abstract: Electromagnetic tracking utilizes the distribution of an electromagnetic field to detect and track a target’s position and attitude in real time. In the electromagnetic tracking system based on the rotating magnetic field, it is necessary to find…

BIBE19718: Comprehensive Care Plan - A Method of Managing Home Rehabilita-tion Care for Patients with COPD
Guanzhong Yang, Chuifeng Kong
Abstract: Chronic obstructive pulmonary disease (COPD) is a chronic disease with long duration and repeated attacks that is dif-ficult to cure and requires long-term treatment and care. We propose a new patient-centered chronic disease manage-ment…

BIBE19787: Simulation study of biatrial conduction via different conduction pathways in atrial fibrillation
Zhao-lian OUYANG, Li-ping SUN, Hui CHI, et al.
Abstract: Atrial fibrillation (AF) is the most common sustained arrhythmia in clinical practice. Previous simulation show that in normal sinus rhythm, different conduction pathways have great impact on the biatrial conduction patterns…

BIBE17001: Preliminary Study of the Robotic Couch for Prostate Cancer in Proton /Heavy ion Therapy
Yong-de Zhang, Xue-song Dai, Shi-jie Guo
Abstract: In the process of proton/heavy ion radiotherapy, the position of patients requires dynamic adjustment to improve the accuracy of proton/heavy ion radiation. For flexible adjustment…

BIBE16546: Optimization of Oxygen Mass Transfer in a Bio-artificial Liver Support System Based on an Oxygen Carrier
Changzhe Wu, Cheng Zhang, Guanghao Zhang and Xiaolin Huo
Abstract: This study demonstrates that providing an appropriate dissolved oxygen concentration (DO), pH, and temperature for hepatocytes in a bioreactor improves the performance of bio-artificial liver support systems (BALSS)…

BIBE11914: The multiple therapeutic mechanisms of curcumin against cancers
Xiaoping Wang, Qiaoxia Wang, Huanping Lin, Haolin Wang
Abstract: Due to the prevalence of cancer, efficacious therapies with a good safety profile, and low toxicity are essential. There-fore, it is necessary to look for some drugs which are safety, low toxicity and efficient…

BIBE15815: Complete canonical correlation analysis for multi-omic molecular sub-typing of colorectal cancer
Lin Qi, Wei Wang, Xianglei Xing, Kejun Wang and Xin Wang
Abstract: Colorectal cancer (CRC) is one of the most commonly diagnosed cancers, and one of the leading causes of cancer-related death [1, 2]. Similar to other major malignancies, colon cancer is a heterogeneous…

BIBE19371: Online dictionary learning based on subject connectivity in fMRI data
Zhe Gao, Hang Zhang, Li Yao, Zhiying Long
Abstract: Functional magnetic resonance imaging (fMRI) based on the hemodynamic response has been widely used to investi-gate the functional connectivity relationships between the brain…

BIBE16485: Oscillating field stimulation inhibits astroglial scar formation in spinal cord injured rats
Cheng Zhang, Guanghao Zhang, Changzhe Wu and Xiaolin Huo
Abstract: Objectives: We investigated how oscillating field stimulation (OFS) would affect astroglial scar formation and astrocyte activation following spinal cord injury (SCI) in rats. Methods: SD rats were divided into…

BIBE11369: Error-minimization approach to reduce protease bias
Chong Chen, Haoran Zheng
Abstract: The main goal in proteomics is to describe the proteome in a comprehensive and accurate way, and enzymolysis is a key step in the process of large-scale proteomics experiments. For the same protein samples…

BIBE11571: Analysis and correction of error of magnetic particle spectroscopy
Dongxu Yang, Xinran Wei, Ming Wang
Abstract: The impact of inhomogeneous distribution of physical quantities on magnetic particle spectroscopy are analyzed in three cases by simulation, electromagnetic interference and inhomogeneous…

BIBE13201: A design of surgical robotic system based on 6-DOF parallel
Binbin Chen, Qixin Cao, Weibang Bai
Abstract: A surgical robotic system which can be applied to do the adjustment work of surgical instruments is introduced in this paper, whose purpose is to change the manual operation way to more efficient…

BIBE12652: An Objective-driven Analyses Framework Utilizing the Characters of Medical Big Data: the Roles Anti-platelet Agents Play in the Associa-tions between Hypertension and Stroke as an Application
Yingying Wang, Qi Li, Jiandong Zhang, et al.
Abstract: The fast developments of big data have brought great opportunities and challenges to different fields including medicine. The ‘volume, velocity, variety, and veracity’ characters of medical big data may identify relationships between patients that a single data set alone can not discover. Compared with the traditional…

BIBE19725: Disturbed Brain Anatomical Networks and Functional Directed Connection in Temporal Lobe Tumor Patients based on DTI and Resting-state fMRI
Haipeng Huang, Li Xue, Ling Tao, Yuxuan Yang, Zhiyu Qian
Abstract: This study aims to apply graph theory measures of fiber tracking derived from diffusion tensor imaging (DTI) and resting-state fMRI data to investigate the cognitive alternation and functional restructuring mechanism in patients…

BIBE14382: In silico study of Pb++ effects on ventricular action potential, as an air particulate matter component of Medellin city
Catalina Tobón, Robison Buitrago-Sierra, Laura C Palacio, Javier Saiz
Abstract: Exposure to air pollution promotes the occurrence of cardiovascular diseases. Particulate matter (PM) is considered the most severe pollution problem due to can affect the heart and cause serious health problems…

BIBE14884: Study on the druggability of IDPs and theirs virtual screening
Zuowei Mao
Abstract: Intrinsically disordered proteins (IDPs) are widespread in nature, and they were found to have important biological functions, which are associated with various human diseases. Therefore, the research of IDPs…

BIBE14712: Structures and properties of novel fluorescent antifolates targeted with Folate Receptor α studied by DFT and MD simulations
Yue Jiang, Cuihong Wang, Xuening Fei, Yingchun Gu
Abstract: We designed four novel fluorescent antifolates. The structural and orbital properties of the compounds were analyzed by the density functional tight-binding method. The four compounds were used to dock with…

BIBE18889: Exploratory research of the anesthetic method for straight tube-shaped tracheal stent implantation
Dongmei, Li, Hanlei, Zhang, Guoqing, Zhao, Kai, Li, Longyun, Li
Abstract: Objective: To explore research on the security and effect of conscious sedation combined with local anesthesia used for tracheal stent implantation, the operation of which has strong stimulation and a high rate of hypoxemia…

BIBE19836: Multiclass Classification of Vertebral Pathologies with Limited Data
Liyuan Zhang, Jiashi Zhao, Huamin Yang, Zhengang Jiang, Shi Weili
Abstract: For intelligent diagnosis of vertebral pathologies, the available labeled data are usually limited and the discrimination of multiple lesions is not obvious. To deal with this issue, a novel multiclass classification…

BIBE12303: Learning End-to-end Diagnostic Policy for Passive Rehabilitation Robot with Deep Learning
Peiyuan Ni, Wenguang Zhang, Kaixiang Hu, Peifei Wang, Qixin Cao
Abstract: For passive rehabilitation robots with low costs and simple systems, their control policies require to be adjusted manually. Moreover, the state variables for the policies also require to be defined by human…

BIBE12346: Motion-Recognition System with Dual-Processor Using Threshold-Based Algorithm
Yunkun Ning, Cuiju Xiong, Weimin Xiong, Huiqi Li and Guoru Zhao
Abstract: Due to the decline of physical function, the elderly may suffer from falls which are the major cause ofstroke, paralysis or even death. This paper presents a motion-monitoring device based on MTK+STM32 dual-processor. The device uses…

BIBE14718: Development of Knowledge-based Ontology Framework for Diabetes Patients in Medical Applications
Li Chen, Dongxin Lu, Sandeep Pirbhulal, et al.
Abstract: Diabetes is a disease that affects an estimated 422 million adults, and the total costs of diagnosed diabetes have raised more than $245 billion. The main limitations of existing, ontology-based methods…

BIBE19824: Study on composite magnetic field device for biological effect of elec-tromagnetic field
Xinran Wei, Dongxu Yang, Ming Wang
Abstract: A composite magnetic field device is proposed in this paper that can produce a composite magnetic field, even a sin-gle magnetic field. The device is usually applied to the study of electromagnetic field…

BIBE18771: The anti-inflammation and anti-oxidation effects of velvet antler poly-peptides on osteoarthritic chondrocytes in rabbits
XIA LI, JILE XIN, HUAN GU, et al.
Abstract: Background: The deer velvet antler is a well known Traditional Chinese Medicine that widely used in China for thou-sands of years. It had been recorded that deer velvet antlers strengthen the human body…

BIBE13551: LncRNA NONRATT021972 involved in SD rats with type 2 diabetes
Kai Li, Xiao-xuan Du, Gang Liu
Abstract: Objective: To explore potential of LncRNA NONRATT021972 in diabetic neuropathic pain and investigate detailed mechanism in rat models. Methods Streptozocin (STZ) was treated for Sprague Dawley…

BIBE15663: Low-positive pressure ventilation system improves non-hypoxemic apnoea tolerance
Kai Li, Shan-shan Yu, Yuan Jiao
Abstract: Objective: To determine pre-oxygenation with PSV increases the duration of non-hypoxemic apnoea in non-obese patients. Method: 50 patients scheduled pan-endoscopy were enrolled to receive…

BIBE17015: EEG-based Mental Fatigue Trend during Watching 3DTV
Chunxiao Chen, Jing Wang, Jian Li, Xiong Lu
Abstract: Mental fatigue caused by prolonged watching of 3DTV in various fields has been focused on the stereoscopic display. Electroencephalogram (EEG) is an objective technique that can be used to…

BIBE17708: Anesthetic effect of midazolam in endoscopic retrograde cholangi-opancreatography
Lin Zuo, Guoqing Zhao, Longyun Li, Shan Lu, Kai Li
Abstract: Background: Endoscopic retrograde cholangiopancreatography (ERCP) is an advanced upper endoscopic procedure, and is useful for the diagnosis and treatment of pancreatobiliary…

BIBE18882: Characteristics of vanillin adsorption onto fresh calcium phosphate in sucrose solution
Shanguang Wu, Xiangli Xu, Yuhong Tian, Na Liao, Tingfan Tang
Abstract: The adsorption of vanillin onto fresh calcium phosphate was studied. The adsorption kinetic was tested and the kinetic data were best described by the pseudo-second order model…

BIBE14213: A one-chip solution for wireless capsule endoscopes with a potential wireless power transfer module
Liang Li, Jun Ma, Jingjing Wang, et al.
Abstract: Implantable medical devices have witnessed their success in recent years. As one of the most feasible devices, wireless capsule endoscope (WCE) draws more research attention…

BIBE12078: Intelligent wheelchair research based on SSVEP Brain - Computer-Interface
GaoNuo, ZhaiWenwen, Lu Jiaxing, Lu Shouyin, TianYa
Abstract: In this paper, a Brain Computer Interface (BCI) based intelligent wheelchair is described. The proposed wheelchair uses the SSVEP (Steady State Visual Evoked Potential) as the control signal…

BIBE19257: Combination therapy of chitosan conduit and naringin facilitate re-generation of injured sciatic nerve in rats
Wei Rong, Xu Cai, YongWei Pan, Fei Song, Cheng Zhang, SongHua Xiao
Abstract: Objectives: To explore the feasibility of combining chitosan conduits filled with naringin to repair peripheral nerve de-fects in rats．Methods: A total of 90 Sprague-Dawley rats were used, a 5mm nerve defect was created in left…

BIBE19519: Evaluation of Position Tracking Based Control System for Robotic Assisted Minimally Invasive Surgery System
Liang Xiong, Jianting Fu, Yang Xiang, Yi Xie
Abstract: Robotic assisted minimally invasive surgery (RAMIS) overcomes most of the drawbacks of traditional minimally invasive surgery, and is widely used around the world. However, hysteresis caused by mechanism and control system…

BIBE13081: EEG Signals Classification of Motor Imagery based on Multi-Feature Description
Gao Nuo, Lu Hao, Wu Linyan and Lu Shouyin
Abstract: Electroencephalogram (EEG) based Brain Computer Interface (BCI) provides a new communication and control channel for people with severe motor disabilities. Motor imagery analysis is one of the widely used methods…

BIBE12950: Study on the dynamic position of nucleosome in different attribute genes under environmental pressure
Jihua Feng, Huazheng Yu, Jing Chen, Yaru Guo, Jin Mou, Ke Liu et al.
Abstract: The eukaryotic nucleosome positioning is dynamic in environmental changes, and their moving patterns on different transcription level genes are varied. We divided the yeast nucleosome occupancy data into different groups…

BIBE14331: The Distribution Characteristics of Nucleosomes on Different Expression Patterns and Specific Functional Genes in Drosophila Genome
Jihua FENG, Jing CHEN, Huazheng YU et al.
Abstract: In this paper, we analysed the characteristics of nucleosomes distribution on the different expression patterns and specific functional genes families in the Drosophila embryonic genome. The results suggested that the location…

BIBE11248: An Apparatus for On-Line Estimation and Visualization of Joint Torque from Surface EMG
Jiantin Fu, Yang Xiang, Liang Xiong, and Yi Xie
Abstract: A novel measurement system has been developed to record surface Electromyography (sEMG) of muscles and their corresponding joint torques in real-time. In this article, we recorded sEMG of forearm muscles…

BIBE13372: Effects on Cells of the 44.5 kDa Outer Membrane Proteins Isolated and Cloned from Bovine Fusobacterium necrophorum (AB)
Jing Xu, Han Gao, Qiao-Dan Qi, Yan Shi, Hong-Yan Guo et al.
Abstract: Fusobacterium (F.) necrophorum (AB), a gram-negative obligate anaerobe, a kind of conditional pathogens, is often into organism with Corynebacterium pyogenes and Staphylococcus aureus and is the main pathogens…

BIBE18876: Maximal Information Coefficient on Comparative Analysis of Identifying Differentially Expressed Genes in Citrus Huanglongbing Disease
Qiu Wenfeng, Liu Hanming
Abstract: Citrus Huanglongbing disease is a devastating plant disease in the world. By an analysis of high-throughput gene ex-pression profiling, it could insight the influence of the Candidatus liberibacter on biological processes…

BIBE18760: A Novel Algorithm Based on Hanning-Windowed Tri-Section Independent Component Analysis for Remote Heart Rate Detection
Haitao Chen, Qinyuan Wei, Lai Wei, and Xiaohui Duan
Abstract: Non-contact heart rate detection can simplify physiological parameters measurement without the invasion of electrodes. In this paper, we provide a novel algorithm based on Hanning Window and Independent Component…

BIBE13093: Invalid Patents analysis of Magnetic Resonance Imaging Based on Orbit
Ruyi Luo
Abstract: Invalid patents contain rich technical and market information, mining invalid patents’value is an important path to study MRI technology. Based on the Orbit patent analysis system of QUESTEL in France, this paper analyzed MRI invalid…

BIBE19076: Continuous using of antimicrobial agents less than 6 months or using non-fluoroquinolone antimicrobial agents reduced the occurrence of spontaneous bacterial peritonitis and improved the survival rates in cirrhosis: A meta-analysis
Li-hui Long, Ya-ting Lv, Li Xu, Jun-jun Mao, Li Wang
Abstract: Objective: To systematically investigate the effects of the continuous use time and the types of antibacterial drugs in reducing the incidence of spontaneous bacterial peritonitis (SBP) and the mortality rates in liver cirrhosis patients…

BIBE16026: Analysis of BOLD fMRI Signal Preprocessing Pipeline on Different Datasets while Reducing False Positive Rates
Yunxiang Ge, Yu Pan, Weibei Dou
Abstract: The technology of functional Magnetic Resonance Imaging (fMRI) based on Blood Oxygen Level Dependent (BOLD) signal has been widely used in clinical treatments and brain function researches. The BOLD signal has to be…

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